Robby Bowles

Engineering Musculoskeletal Cell Systems with CRISPR Gene Activators and Repressors

Abstract:

The development of cell therapies, gene therapies, and tissue engineering strategies has the potential to change how we treat and think about musculoskeletal disorders. At the center of these development efforts has been the question of how best to control cells and their function. With the development of novel CRISPR systems, we are now better able to control cell phenotype and function than we have been able to before. In this talk, we will explore my labs efforts to better understand the source of back pain using CRISPR gene activators and repressors and our development of novel cell and gene therapies to treat back pain and musculoskeletal disorders more broadly.

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